I wrote to Alice Flaherty, expert on the neurology of writing, for help with references on the neurology of math. She suggested some places to look and some search terms, so I've been playing with PubMed and discovering interesting things such as that a lot more seems to be known about the neurology of metaphor than about the neurology of math. I came across a couple of articles with interesting descriptions which I though I'd share:
Ethical Hum Sci Serv. 2000 Fall-Winter;2(3):181-92.
Research into the origins and characteristics of unicorns: mental illness as the unicorn.
Kingsborough Community College, City University of New York, USA.
Basic research, particularly into the psychological and neurological underpinnings of schizophrenia and other "mental illnesses," is flawed because of its adherence to the ideology that unwanted, hard-to-understand behavior constitutes true medical illness. It is argued here that psychiatric diagnostic terms represent moral judgments rather than medical entities. By reducing experimental subjects to a moral label, and assuming that neurological differences associated with unwanted behavior are brain diseases, researchers fail to take into account the conscious experience, organization of self and self-image, patterns of motivation, history and social contexts of their patients. The failure to consider the psychology of their subjects renders the results of these studies ambiguous and irrelevant for any uses except bolstering the biomedical model of psychiatry.
PMID: 15278984 [PubMed - indexed for MEDLINE]
(I had recently noticed that the literature associated with various conditions affecting the social skills is often contaminated by the researchers' dislike of the research subjects.)
Neurosci Lett. 2005 Jan 3;373(1):5-9.
Neural activity associated with metaphor comprehension: spatial analysis.
Sotillo M, Carretie L, Hinojosa JA, Tapia M, Mercado F, Lopez-Martin S, Albert J.
Departamento de Psicologia Basica, Facultad de Psicologia, Universidad Autonoma de Madrid, 28049 Madrid, Spain.
Though neuropsychological data indicate that the right hemisphere (RH) plays a major role in metaphor processing, other studies suggest that, at least during some phases of this processing, a RH advantage may not exist. The present study explores, through a temporally agile neural signal--the event-related potentials (ERPs)--, and through source-localization algorithms applied to ERP recordings, whether the crucial phase of metaphor comprehension presents or not a RH advantage. Participants (n=24) were submitted to a S1-S2 experimental paradigm. S1 consisted of visually presented metaphoric sentences (e.g., "Green lung of the city"), followed by S2, which consisted of words that could (i.e., "Park") or could not (i.e., "Semaphore") be defined by S1. ERPs elicited by S2 were analyzed using temporal principal component analysis (tPCA) and source-localization algorithms. These analyses revealed that metaphorically related S2 words showed significantly higher N400 amplitudes than non-related S2 words. Source-localization algorithms showed differential activity between the two S2 conditions in the right middle/superior temporal areas. These results support the existence of an important RH contribution to (at least) one phase of metaphor processing and, furthermore, implicate the temporal cortex with respect to that contribution.
PMID: 15555767 [PubMed - indexed for MEDLINE]
Brain Res Cogn Brain Res. 2004 Aug;20(3):395-402.
Neural correlates of metaphor processing.
Rapp AM, Leube DT, Erb M, Grodd W, Kircher TT.
Department of Psychiatry, University of Tuebingen, Osianderstrasse 24, D-72076 Tuebingen, Germany. Alexander.Rapp@med.uni-tuebingen.de
Metaphoric language is used to express meaning that is otherwise difficult to conceptualize elegantly. Beyond semantic analysis, understanding the figurative meaning of a metaphor requires mental linkage of different category domains normally not related to each other. We investigated processing of metaphoric sentences using event-related functional magnetic resonance imaging (fMRI). Stimuli consisted of 60 novel short German sentence pairs with either metaphoric or literal meaning. The pairs differed only in their last one to three words and were matched for syntax structure, word frequency, connotation and tense. Fifteen healthy subjects (six female, nine male, 19-51 years) read these sentences silently and judged by pressing one of two buttons whether they had a positive or negative connotation. Reading metaphors in contrast to literal sentences revealed signal changes in the left lateral inferior frontal (BA 45/47), inferior temporal (BA 20) and posterior middle/inferior temporal (BA 37) gyri. The activation in the left inferior frontal gyrus may reflect semantic inferencing processes during the understanding of a metaphor. This is in line with the results from other functional imaging studies showing an involvement of the left inferior frontal gyrus in integrating word and sentence meanings. Previous results of a right hemispheric involvement in metaphor processing might reflect understanding of complex sentences.
PMID: 15268917 [PubMed - indexed for MEDLINE]